Induction of Chemokine and Cytokine Responses byHelicobacter pyloriin Human Stomach Explants
- 1 January 2001
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 36 (10) , 1022-1029
- https://doi.org/10.1080/003655201750422602
Abstract
Background: The cytokine response during the acute phase of Helicobacter pylori infection in humans has not been studied. The aim of this study was therefore to investigate the early cytokine responses against H. pylori using cultured human stomach explants as a model of acute infection. Methods: Gastric corpus tissue obtained from 13 adult uninfected and 3 H. pylori-infected patients undergoing gastric surgery due to obesity was used for preparation of mucosal explants. The cultured explants were exposed to different H. pyloriKeywords
This publication has 14 references indexed in Scilit:
- Inflammatory Cytokine mRNA Expression during Early and PersistentHelicobacter pyloriInfection in Nonhuman PrimatesThe Journal of Infectious Diseases, 2000
- Cytokine Expression and Production by PurifiedHelicobacter pyloriUrease in Human Gastric Epithelial CellsInfection and Immunity, 2000
- Pathophysiology of Helicobacter pylori-induced Gastritis and Peptic Ulcer DiseaseThe American Journal of Medicine, 1997
- Molecular mimicry between Helicobacter pylori and the hostTrends in Microbiology, 1997
- Cytokine gene expression in Helicobacter pylori associated antral gastritis.Gut, 1994
- Neutrophil Activation by Helicobacter pylori LipopolysaccharidesThe Journal of Infectious Diseases, 1994
- Helicobacter pylori Infection and Gastric LymphomaNew England Journal of Medicine, 1994
- Agonists and antagonists for lipopolysaccharide-induced cytokinesImmunobiology, 1993
- Acute Helicobacter pylori infection: clinical features, local and systemic immune response, gastric mucosal histology, and gastric juice ascorbic acid concentrations.Gut, 1991
- Characterization of the Helicobacter pylori urease and purification of its subunitsMicrobial Pathogenesis, 1991