Medullary CD30+ T cell lymphoma with eosinophilia and hyper-IgE supervening during the relentless course of pityriasis lichenoides.
- 14 April 2000
- journal article
- case report
- Published by S. Karger AG in Dermatology
- Vol. 200 (2) , 170-172
- https://doi.org/10.1159/000018358
Abstract
We report a case of extensive pityriasis lichenoides exhibiting a relentless course. PUVA therapy and oral retinoids cleared temporarily the lesions but did not really halt the course of the disease. Eosinophilia and hyper-IgE occurred after 50 years of evolution. An aggressive medullary CD30+ T cell lymphoma without skin involvement was then diagnosed when pityriasis lichenoides became more extensive and necrotic. The disease was rapidly fatal.Keywords
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