Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult
- 28 June 2004
- journal article
- case report
- Published by Springer Nature in Acta Neurochirurgica
- Vol. 146 (9) , 1033-1038
- https://doi.org/10.1007/s00701-004-0313-5
Abstract
A 22-year-old man presented with a rare case of atypical teratoid/rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.Keywords
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