Studies of Foetal Death and Foetal Weight in Guinea Pigs Fed Polychlorinated Biphenyls (PCB)
- 1 February 1982
- journal article
- research article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 50 (2) , 100-103
- https://doi.org/10.1111/j.1600-0773.1982.tb00948.x
Abstract
Pregnant guinea pigs were fed a total dose of 100 mg of the commercial PCB preparation Clophen A50 during days 16 to 60 of gestation. This treatment caused severe foetal, but no maternal, death. Contrarily, a total dose of 25 mg or 100 mg of 2,2′,4,4′,5,5′‐hexachlorobiphenyl (HCB) did not cause foetal death in the guinea pig. The prenatal growth rate was increased by a total dose of 25 mg, but not by 100 mg, of HCB.Keywords
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