Comparison of the properties of a normal and base deactivated bonded silica gel for the solid phase extraction of [14C]-propranolol
- 1 January 1995
- journal article
- Published by Royal Society of Chemistry (RSC) in Analytical Proceedings including Analytical Communications
- Vol. 32 (5) , 179-181
- https://doi.org/10.1039/ai9953200179
Abstract
The properties of a newly introduced, base deactivated, C8 bonded, silica gel for solid phase extraction have been assessed using the drug propranolol. The compound was extracted from aqueous buffer and dog plasma. The properties of this new material have been compared with those of a conventional C18 bonded material. These studies have shown that whilst both types of phase give high extraction efficiencies, the recovery profiles from the two types of cartridge obtained with methanol and acetonitrile as eluents are quite different.Keywords
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