Involvement of the p16INK4 (CDKN2) gene in familial melanoma
- 1 April 1996
- journal article
- review article
- Published by Wolters Kluwer Health in Melanoma Research
- Vol. 6 (2) , 139-146
- https://doi.org/10.1097/00008390-199604000-00009
Abstract
Recent work on the molecular genetics of familial melanoma has suggested that the p16 kinase inhibitor gene (CDKN2) is one of the genes causing familial melanoma. Evidence for the candidacy of the p16 gene as a familial melanoma gene is summarized and the characteristics of this class of cell cycle control proteins are reviewed.Keywords
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