Ethanol and the Nervous System

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Abstract
ALCOHOLISM is a major social, economic, and public health problem throughout much of the world. In the United States alone, the annual cost of lost productivity and health expenses related to alcoholism is estimated to be $117 billion.1 Ethanol-related neurologic disorders constitute a particularly large, diverse, and devastating subset of the medical complications of alcoholism. The frequency of such disorders reflects ethanol's widespread use; more puzzling is the great variety of these disorders, which may involve virtually any level of the nervous system. Not everyone who consumes ethanol to excess has neurologic complications, nor is it clear why a particular . . .