Interdependence of regional expiratory flow
- 1 December 1985
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 59 (6) , 1924-1928
- https://doi.org/10.1152/jappl.1985.59.6.1924
Abstract
Flows from different lung regions interact at the junctions of the bronchial tree, and flow from each region depends on the driving pressures for other regions. At each junction, flow from the region with the higher driving pressure is favored. As a result there is a limit on the difference in alveolar pressures that can develop during expiratory flow from a lung with regional differences in lung compliance and airway resistance. The limiting pressure difference is smaller for lower flow. A nonuniform lung therefore empties more uniformly if it empties slowly, and maximum flow at low lung volume may be greater than it would be at the same lung volume during a maximal expiratory vital capacity maneuver.This publication has 3 references indexed in Scilit:
- Density dependence of maximal flow in dogs with central and peripheral obstructionJournal of Applied Physiology, 1983
- Time dependence of maximum flow as an index of nonuniform emptyingJournal of Applied Physiology, 1979
- Determinants of maximal expiratory flow from the lungs.Journal of Applied Physiology, 1967