Protease and EGF1 Domains of Factor IXa Play Distinct Roles in Binding to Factor VIIIa
Open Access
- 1 June 1999
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 274 (26) , 18477-18486
- https://doi.org/10.1074/jbc.274.26.18477
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Replacing the first epidermal growth factor-like domain of factor IX with that of factor VII enhances activity in vitro and in canine hemophilia B.Journal of Clinical Investigation, 1997
- Interaction of Calcium with Native and Decarboxylated Human Factor X.Journal of Biological Chemistry, 1997
- Ca2+ Binding to the First Epidermal Growth Factor-like Domain of Human Blood Coagulation Factor IX Promotes Enzyme Activity and Factor VIII Light Chain BindingPublished by Elsevier ,1996
- Structural Integrity of the γ-Carboxyglutamic Acid Domain of Human Blood Coagulation Factor IXa Is Required for Its Binding to Cofactor VIIIaPublished by Elsevier ,1996
- Localization of Factor IXa and Factor VIIIa Interactive SitesJournal of Biological Chemistry, 1995
- The coagulation cascade: initiation, maintenance, and regulationBiochemistry, 1991
- Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six speciesGenomics, 1990
- Characterization of three abnormal factor IX variants (Bm Lake Elsinore, Long Beach, and Los Angeles) of hemophilia-B. Evidence for defects affecting the latent catalytic site.Journal of Clinical Investigation, 1985
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970