Inhibition of Immune Responses in Vitro by Specific Antiserums to Ia Antigens
- 18 April 1975
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 188 (4185) , 268-270
- https://doi.org/10.1126/science.1118728
Abstract
Mouse antiserums prepared against Ia antigens, which are products of I (immune response) region genes of the H-2 complex, can inhibit both primary (immunoglobulin M) and secondary (immunoglobulin G) immune responses in vitro by mouse spleen cultures to heterologous erythrocytes. Antiserums directed specifically at products of either the H-2K or H-2D loci have no effect on this response.Keywords
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