Infrared study of hydrogen bonds involving N‐heterocyclic bases and phenols

Abstract
The hydrogen bond complexes between phenols and N‐heteroaromatic bases 2,4,6‐tri(2‐pyridyl)‐1,3,5‐triazine, 2,2′,2′‐terpyridine, quinoxaline, pyrido[2,3‐b]pyrazine, pyzazino [2,3f]quinoxaline and 5‐nitrozphenanthroline are investigated by infrared spectroscopy in 1,2‐dichloroethane. The stability constants of the complexes involving N‐heteroaromatic bases characterized by tow vicinal nitrogen atoms having lone pairs pointing to each other are higher than predicted from their basicity. Possible differences between protonation and hydrogen bond formation are discussed. Nheteroaromatic bases such as tri(2‐pyridyl)‐1,3,5‐triazine or phenanthrolines cannot be considered as proton sponges but their behaviour is intermediate between that of the classical heteroaromatic bases and the proton sponges.

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