Prostaglandin synthesis: design and execution
- 1 January 1973
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- Vol. 22, 2796-2804
- https://doi.org/10.1039/p19730002796
Abstract
Application of the principles of synthesis design to the problem of prostaglandins led to many possible routes, including one commencing with endo-dicyclopentadiene. This starting material was then converted into racemic prostaglandin F2α in a minimum often stages via bicyclo[3.3.0]octane intermediates.Keywords
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