Effects of X Irradiation on Renal Function in Newly-Hatched Chicks

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Abstract
Young chicks were exposed to 1000 r X-radiation at dose rates of 6 or 43 r per min. Detns. of excretion rate of urate and phenol red and of blood urate levels indicated that death in the initial period (within 8-24 hrs.) following high rate exposures was preceded by renal failure and a rapidly developing azotemia. Individuals that survived 24 hrs. or more after exposure, whatever the dose rate, continued to excrete at a normal rate. Phenol red retention invariably accompanied failure of urate excretory function.

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