Influence of intratubular pressure on proximal tubular compliance and capillary diameter in the rat kidney
- 1 November 1979
- journal article
- research article
- Published by Springer Nature in Pflügers Archiv - European Journal of Physiology
- Vol. 382 (2) , 179-187
- https://doi.org/10.1007/bf00584220
Abstract
Tubular compliance is the response of tubular diameter to changes in intratubular pressure [7]. Proximal tubular compliance was determined directly by measurements of tubular diameter and pressure and indirectly using a mathematical model of tubular fluid flow based on measurements of the hydraulic pressure gradients along the tubule under free flow conditions and during an induced pressure reduction at the end of the proximal tubule. The two independent methods yielded similar values for compliance. Proximal tubular complicance was found to depend upon the intratubular pressure: tubular compliance was significantly higher (P0.8). Intratubular pressure changes resulted in inverse changes in the diameters of the adjacent capillaries, suggesting that the peritubular capillaries are distensible structures.Keywords
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