Linkage between the loci for the Lp(a) lipoprotein (LP) and plasminogen (PLG)
- 1 May 1988
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 79 (1) , 80-82
- https://doi.org/10.1007/bf00291716
Abstract
A locus, LP, that determines quantitative variation of Lp(a) lipoprotein phenotypes is linked to the plasminogen (PLG) locus (peak lod score =12.73). This linkage relationship assigns a locus with alleles that have an affect on risk for coronary artery disease to the long arm of chromosome 6.This publication has 20 references indexed in Scilit:
- Equine marker genes: Polymorphism for plasminogenAnimal Blood Groups and Biochemical Genetics, 2009
- cDNA sequence of human apolipoprotein(a) is homologous to plasminogenNature, 1987
- Black-white differences in serum Lp(a) lipoprotein levelsClinica Chimica Acta; International Journal of Clinical Chemistry, 1987
- Lp(a) glycoprotein phenotypes. Inheritance and relation to Lp(a)-lipoprotein concentrations in plasma.Journal of Clinical Investigation, 1987
- Partial amino acid sequence of apolipoprotein(a) shows that it is homologous to plasminogen.Proceedings of the National Academy of Sciences, 1987
- Free and Apo B-associated Lpa-specific protein in human serumClinica Chimica Acta; International Journal of Clinical Chemistry, 1987
- Fat feeding in humans induces lipoproteins of density less than 1.006 that are enriched in apolipoprotein [a] and that cause lipid accumulation in macrophages.Journal of Clinical Investigation, 1986
- Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1985
- Linkage relationships of Lp and Ag serum lipoproteins with 25 polymorphic markersHuman Genetics, 1977
- A NEW SERUM TYPE SYSTEM IN MAN—THE Lp SYSTEMActa Pathologica Microbiologica Scandinavica, 1963