THE ELIMINATION AND DISTRIBUTION OF COMPONENTS OF WELDING FUMES FROM LUNG DEPOSITS IN THE GUINEA PIG
- 1 January 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Annals of Occupational Hygiene
- Vol. 22 (1) , 33-41
- https://doi.org/10.1093/annhyg/22.1.33
Abstract
The fate of metallic element components of welding fume particles deposited in the lungs of guinea pigs has been studied by radioactive labelling produced by prior neutron activation of the material. Neutron irradiated material, collected from fumes of metal inert gas welding using stainless steel wire, was administered by intratracheal injection. The elimination pattern of elements from the lung deposits was established by a whole body and thoracic scanning technique in vivo and by analysis of radioactivity in faeces and urine. Distribution of components in major organs and blood was determined by analysis of tissue samples post mortem . Major elimination was via the gastrointestinal tract and some systemic distribution of soluble components of iron, chromium, cobalt and nickel occurred via the blood.This publication has 0 references indexed in Scilit: