SPERM SIZE ABNORMALITIES IN HOMOZYGOUS AND HETEROZYGOUS In(5)9Rk MICE
- 1 March 1979
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Genetics and Cytology
- Vol. 21 (1) , 115-119
- https://doi.org/10.1139/g79-015
Abstract
Sperm abnormalities were scored in In(5)9Rk homozygotes, heterozygotes and in the inbred strains, C57BL/6J, C3H/HeJ, DBA/2J and JUFaCt, used to produce the heterozygotes. The sperm abnormalities of the inversion heterozygotes were remarkable, about 40% were either double-headed or abnormally large in size. The double-headed sperm had head dimensions similar to those of normal-sized sperm, but the large sperm heads were 1.2 times longer and 1.3 times wider and presumably had twice the usual nuclear volume. This observation suggests that the anaphase bridge formed in inversion heterozygotes resulting from the paracentric inversion may constitute an impediment to cytokinesis and may lead to two genomes being packaged into a single sperm. If this is a general phenomenon, sperm morphology may provide a useful screen for paracentric inversions.This publication has 6 references indexed in Scilit:
- X-RAY INDUCED PERICENTRIC INVERSIONS IN ANOPHELES ALBIMANUSCanadian Journal of Genetics and Cytology, 1977
- Chemical induction of sperm abnormalities in mice.Proceedings of the National Academy of Sciences, 1975
- TERATOSPERMIA AND CHROMOSOMAL-ABNORMALITIES1975
- VARIATION OF THE DNA CONTENT OF MORPHOLOGICALLY NORMAL AND ABNORMAL SPERMATOZOA IN MICE SUSCEPTIBLE TO IRREGULAR MEIOTIC SEGREGATIONReproduction, 1974
- Producing and detecting paracentric chromosomal inversions in miceMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1971
- ORIGINE DES SPERMATOZOÏDES DIPLOÏDES PRÉSENTS DANS L'ÉJACULAT D'UN TAUREAU CHAROLAISAnnales de Biologie Animale Biochimie Biophysique, 1967