Intestinal Hydrolysis and Conjugation of a Pesticidal Carbamate in vitro
- 2 October 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 170 (3953) , 77-78
- https://doi.org/10.1126/science.170.3953.77
Abstract
The metabolite 1-[1-14C]naphthyl glucuronide was isolated from mucosal and serosal fluids of everted sacs of rat small intestine incubated in media containing either the insecticide 1-[1-14C]naphthyl N-methylcarbamate (carbaryl) or 1-[1-14C]naphthol. The hydrolysis of carbaryl and conjugation of the liberated naphthol indicated some degree of metabolism by the intestine before absorption.Keywords
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