Serum Bile Acids in Man during Vitamin C Supplementation and Restriction
- 12 January 1977
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 202 (1-6) , 283-287
- https://doi.org/10.1111/j.0954-6820.1977.tb16828.x
Abstract
A daily dosage of 5 g ascorbate was given to 14 persons during one month. Various routine biochemical parameters were studied and the concentrations of individual bile acids in serum were determined. A significant increase in chenodeoxy-cholic acid concentration was found on interruption of vitamin C supplementation, whereas no other changes in bile acid concentrations were significant. One person, used to a large ascorbate intake (1 g/day), was deprived of ascorbate. On resuming the high ascorbate intake, serum bile acid concentrations showed an increasing trend. Urinary oxalate excretion and concentrations were impressively increased during vitamin C supplementation but no effects on kidney function were observed.This publication has 15 references indexed in Scilit:
- Reduction of gallstone formation by ascorbic acid in hamstersCellular and Molecular Life Sciences, 1977
- Effect of ascorbic acid on the intestinal absorption of bile salts and metabolism of cholesterol in guinea pigs.CHEMICAL & PHARMACEUTICAL BULLETIN, 1976
- Determination of phosphate in serum and urine by a single step malachite-green methodClinica Chimica Acta; International Journal of Clinical Chemistry, 1975
- Dynamics of the Enterohepatic Circulation of Bile AcidsNew England Journal of Medicine, 1974
- An improved colorimetric procedure for urine oxalateClinica Chimica Acta; International Journal of Clinical Chemistry, 1972
- A Versatile Method for Analysis of Bile Acids in PlasmaAnalytical Letters, 1972
- ATHEROSCLEROSIS AND VITAMIN CThe Lancet, 1971
- ON THE METABOLITES OF ASCORBIC ACID, ESPECIALLY OXALIC ACID, ELIMINATED IN URINE, FOLLOWING THE ADMINISTRATION OF LARGE AMOUNTS OF ASCORBIC ACIDTHE JOURNAL OF VITAMINOLOGY, 1966
- Urinary Oxalate Excretion by Man Following Ascorbic Acid Ingestion.Experimental Biology and Medicine, 1954