A Convenient Method for the Preparation of 6,7-Methyl-Enedioxy-3-Alkyl-2-Hydroxy-1,4-Naphthoquinones from Natural Safrole and Carboxylic Acids
- 1 June 1983
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 13 (8) , 691-699
- https://doi.org/10.1080/00397918308060351
Abstract
As part of our program to prepare substituted rtaphthoquinones with potential biological activity1 we have synthetized 6, 7-methyleriedioxy-3-alky 1 lawsones (5a-g) from natural safrole (1) and carboxylic' acids (∼50% overall yield).Keywords
This publication has 3 references indexed in Scilit:
- One step conversion of aldehydes to estersTetrahedron Letters, 1978
- Über β‐[Oxy‐phenyl]‐äthylamine und ihre Umwandlungen, II. Mitteil.: Synthese weiterer Amine und der entsprechenden [Oxy‐phenyl]‐essigsäuren aus natürlichen AllylverbindungenBerichte der deutschen chemischen Gesellschaft (A and B Series), 1934
- THE ALKYLATION OF HYDROXYNAPHTHOQUINONE. III. A SYNTHESIS OF LAPACHOLJournal of the American Chemical Society, 1927