MULTIPLE PRIMARY NEOPLASMS OF THE ANOGENITAL REGION

  • 1 January 1980
    • journal article
    • research article
    • Vol. 56  (3) , 365-369
Abstract
The anogenital region, comprising the cervix, vagina, vulva, perineum and anus, has the potential for the development of multicentric and multiple primary malignancies. Fifteen patients with 3 or more primary neoplasms in this region are considered. Awareness of the existence of these tumors as a regional disease and the possible long intervals between successive malignancies are emphasized. The presence of a vulvar neoplasm should arouse suspicion of a synchronous primary tumor elsewhere in the region. Conversely, sequential neoplasms occur more commonly after an initial cervical primary neoplasm and should be anticipated.

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