Continuous In-Vivo Estimation of Blood Alcohol
- 1 February 1962
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 8 (1) , 72-79
- https://doi.org/10.1093/clinchem/8.1.72
Abstract
Automated chemical analysis was applied to constant in-vivo experiments on dogs for the determination of blood alcohol. The continuous blood collection was similar to that in earlier experiments for determination of blood glucose in humans. Although interferences by glucose was observed in the chemical methodology used, preliminary data show that the rise of blood alcohol is slower following I.V. administration of alcohol-water mixtures than with alcohol-saline solutions. With the experimental animal under pentobarbital anesthesia, the alcohol equilibrium is reached more rapidly and the elimination period is significantly prolonged.Keywords
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