Regional differences of an NAD(P)H-dependent H2O2-generating enzyme activity in the rat small intestine.
- 1 January 1982
- journal article
- research article
- Published by Japan Society of Histochemistry & Cytochemistry in ACTA HISTOCHEMICA ET CYTOCHEMICA
- Vol. 15 (3) , 379-385
- https://doi.org/10.1267/ahc.15.379
Abstract
Regional differences of an NAD(P)H-dependent H2O2-generating enzyme activity in the rat small intestinal mucosa were investigated electron-cytochemically. The H2O2-generating activity was localized on the apical membrane covering microvilli of intestinal absorptive cells in the duodenojejunum. The activity was weak in absorptive cells at the mitotic area of the villus, becoming higher toward its apex. The spherical membrane covering the absorptive cells, which were in the process of being extruded at the apical extrusion zone exhibited activity. Activity was also noted in the apical cell membrane of goblet cells, although the activity was weaker than that in the absorptive cells. The ileal activity was apparently weaker than that of the duodenojejunum. There apparently are local variations in the NAD(P)H-depending H2O2-generating activity among intestinal epithelial cells.This publication has 1 reference indexed in Scilit:
- FACTORS AFFECTING THE STATE OF INJECTED HORSERADISH PEROXIDASE IN ANIMAL TISSUES AND PROCEDURES FOR THE STUDY OF PHAGOSOMES AND PHAGO-LYSOSOMESJournal of Histochemistry & Cytochemistry, 1964