Gene transfer of antisense hypoxia inducible factor-1 α enhances the therapeutic efficacy of cancer immunotherapy
- 1 April 2001
- journal article
- Published by Springer Nature in Gene Therapy
- Vol. 8 (8) , 638-645
- https://doi.org/10.1038/sj.gt.3301388
Abstract
At the forefront of medicine, Gene Therapy brings you the latest research into genetic and cell-based technologies to treat disease. It also publishes Progress & Prospects reviews and News and Commentary articles, which highlight the cutting edge of the field.Keywords
This publication has 35 references indexed in Scilit:
- The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target.Cancer and Metastasis Reviews, 1998
- Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1Journal of Biological Chemistry, 1996
- Patterns and Emerging Mechanisms of the Angiogenic Switch during TumorigenesisPublished by Elsevier ,1996
- Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1Journal of Biological Chemistry, 1996
- Oxygen sensing and molecular adaptation to hypoxiaPhysiological Reviews, 1996
- Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neckRadiotherapy and Oncology, 1996
- Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.Proceedings of the National Academy of Sciences, 1995
- General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.Proceedings of the National Academy of Sciences, 1993
- Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.Proceedings of the National Academy of Sciences, 1993
- A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.Molecular and Cellular Biology, 1992