Pronase Effect on Pancreatic Beta Cell Secretion and Morphology
- 11 May 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 180 (4086) , 647-649
- https://doi.org/10.1126/science.180.4086.647
Abstract
Pronase at low concentration (4 micrograms per milliliter) produces a reversible increase of glucose-stimulated insulin release in isolated islets of Langerhans. Pronase also affects the ultrastructure of the beta cells by inducing extensive development of tight junctions as well as the accumulation of secretory product within the extracellular spaces.Keywords
This publication has 11 references indexed in Scilit:
- VARIATIONS IN TIGHT AND GAP JUNCTIONS IN MAMMALIAN TISSUESThe Journal of cell biology, 1972
- The dispositions of proteins in the plasma membranes of animal cells: Analytical approaches using controlled peptidolysis and protein labelsBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1972
- THE ULTRASTRUCTURE OF THE NEXUSThe Journal of cell biology, 1970
- A FINE STRUCTURAL ANALYSIS OF INTERCELLULAR JUNCTIONS IN THE MOUSE LIVERThe Journal of cell biology, 1970
- The Correlative Light and Electron Microscopy of the Islets of Langerhans in Some Lower VertebratesArchivum histologicum japonicum, 1970
- Method for the Isolation of Intact Islets of Langerhans from the Rat PancreasDiabetes, 1967
- Fracture faces of frozen membranes.Proceedings of the National Academy of Sciences, 1966
- Immunoassay of insulin with insulin-antibody precipitateBiochemical Journal, 1963
- FINE STRUCTURE IN FROZEN-ETCHED YEAST CELLSThe Journal of cell biology, 1963
- JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIAThe Journal of cell biology, 1963