Scope and stereochemistry of an olefin synthesis from β-hydroxysulphones
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 8,p. 829-834
- https://doi.org/10.1039/p19780000829
Abstract
The synthesis of olefins from β-acyloxy-sulphones by reduction with sodium amalgam in methanol–ethyl acetate can be applied to the preparation of a wide variety of conjugated dienes. When used for the synthesis of 1,2-disubstituted olefins in which the new double bond is either isolated or conjugated, the reaction is highly stereoselective, and leads to the trans-isomers.Keywords
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