Methods for routine calibration of brachytherapy sources.

Abstract
Two types of routine geometry calibrators, the nuclear medicine dose calibrator and a Lucite jig holding a 30-ml external beam ion chamber with the source in a rigid geometry, were compared with open-air measurements for 137Cs, 192Ir and 226Ra brachytherapy sources. The proximity of scattering surfaces in the 2nd apparatus resulted in significant distortion of the buildup effect and deviation from the inverse square law (5-15%). For the dose calibrator, the response/Roentgen was dependent on source energy and source capsule thickness. Approximately 1/2 of the observed variation (27%) in calibration factors was accounted for by differences in filtration among sources. A mathematical logarithm that corrects for these geometric and filtration effects is presented. In addition, the activity assay procedure provided by the manufacturer of the dose calibrator is unsuitable for brachytherapy sources. Steps to overcome these problems are discussed.

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