HUMAN-BLOOD LYMPHOCYTE SUB-POPULATIONS FROM BIRTH TO 8 YEARS

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 39  (1) , 203-207
Abstract
Total lymphocyte counts and the number of SmIg [surface membrane immunoglobulin] positive and E[erythrocyte]-rosetting cells in the blood of 103 healthy Brazilian children, between birth and 8 yr, and 51 healthy adults were compared. A high number of total lymphocytes were observed during the 1st yr of life and decreased thereafter to reach adult values by the age of 7 yr. The proportion of SmIg positive cells was high in the newborn, further increased during the 2nd trimester and remained unchanged up to the end of the 1st yr of life. Thereafter they gradually decreased, reaching adult levels by the age of 3 yr. The percentage of E-rosetting cells was low in the newborn and young children and increased after the 2nd yr of life to reach adult levels by the age of 7 yr. The absolute number of both lymphocyte subpopulations changed with approximately the same pattern as the total lymphocyte counts.