The Effect of Oral Bethanechol Chloride on Voiding in Female Patients with Excessive Residual Urine: A Randomized Double-Blind Study

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Abstract
The usefulness of bethanechol chloride as a therapeutic adjunct in the treatment of patients with residual urine but no obstruction has been questioned. This study, in which oral bethanechol chloride was compared to a placebo in a randomized, double-blind fashion, does not show a significant short-term effect in female patients with persistent elevation in residual urine. No differences were seen in voided volume residual volume, percentage residual volume, mean flow rate and intravesical pressure at 100 ml volume and at maximal capacity when the treatment groups were compared to the group receiving the placebo.