Cellular Deformability during Maturation of the Myeloblast
- 29 October 1970
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 283 (18) , 943-948
- https://doi.org/10.1056/nejm197010292831801
Abstract
The deformability of human marrow granulocytes was measured by cell elastimetry. Myeloblasts and promyelocytes were extremely resistant to deformation when studied with a micropipette 3.5 μ in diameter. Myelocytes were more easily deformed. Polymorphonuclear granulocytes were highly deformable. These studies indicated that cellular viscosity or surface rigidity is appreciably reduced during granulocyte maturation.Keywords
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