Antibiotic Egg Injection to Eliminate Disease I. Effect of Injection Methods on Turkey Hatchability and Mycoplasma meleagridis Infection

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Abstract
M. meleagridis infection in turkey hatching eggs was eliminated by injecting eggs with a combination of tylosin and gentamicin. Hatched F1 and F2 progeny remained free of egg-transmitted infection. Contact exposure was experienced in 1 negative flock. Of the preincubation injection procedures studied, a drilled hole on the small end of the egg was the inoculation site easiest to administer and best tolerated by the embryo. The embryo can tolerate a dose of gentamicin sulfate injected at 10 days of incubation that would be toxic if administered before incubation. Requirements for maintaining progeny free of infection are discussed.