The Use of a Combination of Galectin-3 and Thyroid Peroxidase for the Diagnosis and Prognosis of Thyroid Cancer
- 1 January 2004
- journal article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 122 (4) , 524-531
- https://doi.org/10.1309/uuqt-e505-ptn5-qj7m
Abstract
In this retrospective histologic study, galectin-3 had a sensitivity of 92% (22/24) for papillary thyroid carcinoma and 44% (4/9) for follicular thyroid carcinoma. Thyroid peroxidase (TPO) had a sensitivity of 50% (12/24) for papillary and 11% (1/11) for follicular carcinoma. The combination of galectin-3 and TPO had a sensitivity of 96% (23/24) for papillary and 44% (4/9) for follicular carcinoma.Keywords
This publication has 17 references indexed in Scilit:
- The investigation of galectin-3 in diseases of the thyroid glandActa Endocrinologica, 2003
- Interobserver and intraobserver reproducibility in the histopathology of follicular thyroid carcinomaHuman Pathology, 2003
- Observer Variation of Encapsulated Follicular Lesions of the Thyroid GlandThe American Journal of Surgical Pathology, 2002
- Galectins and cancerBiochimica et Biophysica Acta (BBA) - General Subjects, 2002
- Galectin-3 as a Presurgical Immunocytodiagnostic Marker of Minimally Invasive Follicular Thyroid CarcinomaJournal of Clinical Endocrinology & Metabolism, 2001
- Galectin-3 expression in various thyroid neoplasms and its possible role in metastasis formationHuman Pathology, 2000
- Evaluation of the Monoclonal Antibody Antithyroperoxidase MoAb47 in the Diagnostic Decision of Cold Thyroid Nodules by Fine-Needle AspirationPathology - Research and Practice, 1997
- Expression of galectin-3 modulates T-cell growth and apoptosis.Proceedings of the National Academy of Sciences, 1996
- Thyroid peroxidase immunodetection as a tool to assist diagnosis of thyroid nodules on fine-needle aspiration biopsyActa Endocrinologica, 1994
- Observer Variation in Histologic Classification of Thyroid CancerActa Pathologica Microbiologica Scandinavica Section A Pathology, 1978