Mutagenicity of carbadox and several quinoxaline 1,4-dioxide derivatives.
- 1 January 1980
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 28 (4) , 1347-1349
- https://doi.org/10.1248/cpb.28.1347
Abstract
Carbadox (2-formylquinoxaline 1, 4-dioxide carbomethoxyhydrazone), a feed additive for swine, showed mutagenicity against Salmonella typhimurium TA 98 and TA 100 both in the absence and presence of S-9 mix. The mutagenic activity was stronger than that of quinoxaline 1, 4-dioxide and was close to that of benzo [a] pyrene.Keywords
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