Rearrangements of chromosome region 12q13→q15 in pleomorphic adenomas of the human salivary gland (PSA)

Abstract
Nine of 40 pleomorphic salivary gland adenomas (PSAs) showed clonal aberrations of chromosome 12, with a breakpoint at 12q13→q15. The cytogenetic findings in these cases and those of nine additional cases reported in the literature suggest that this type of aberration is a primary change directly involved in the genesis of PSA.

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