A Novel Antibacterial Diterpene fromPremna schimperi
- 1 April 1990
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 56 (02) , 187-189
- https://doi.org/10.1055/s-2006-960922
Abstract
A novel diterpene, (5R,8R,9S,10R)-12-oxo-ent-3,13(16)-clerodien-15-oic acid, has been obtained from the leaves of Premna schimperi (Verbenaceae) using an anti-microbial bioassay-guided isolation procedure. The diterpene was identified on the basis of spectroscopic data and is active against the Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis in the concentration range 20-25 µg ml-1.Keywords
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