Secondary Deficiency of Vitamin B1 and Riboflavin in the Blacktongue Producing Diet

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Abstract
Thirty-three dogs in 133 attacks of blacktongue were studied in their response to treatment with 1) liver, 2) nicotinic acid alone, 3) adenylic acid from muscle, and 4) nicotinic acid combined with vitamin B1 (thiamin) and vitamin B2 (riboflavin). It is concluded then that under the conditions of these experiments both riboflavin and vitamin B1 (thiamin) are secondary deficiencies of our blacktongue producing diet. It appears also that the dog's requirement for vitamin B1 is markedly increased by repeated attacks of blacktongue.