Enantioselective Synthesis of Novel Functionalised Prolines via [3 + 2] Cycloadditions of a Chiral Azomethine Ylid
- 1 January 1994
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1994 (11) , 925-928
- https://doi.org/10.1055/s-1994-23050
Abstract
The chiral, stabilised azomethine ylid 2 derived from (S)-2-phenylglycinol underwent enantioselective [3 + 2] cycloaddition reactions with a variety of unactivated and monoactivated dipolarophiles. Cycloaddition products were successfully deprotected to give chiral, functionalised proline derivatives.Keywords
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