Macrophage Tumor Cells Can Help to Cure Murine Lymphoma

Abstract
Intraperitoneal injection of immune syngeneic lymphocytes can prolong the survival time of DBA/2 mice bearing SL2 lymphoma. Addition of induced peritoneal macrophages or macrophage-like J774A tumor cells to the immune lymphocytes enchanced this antitumor effect. Enhancement of antitumor activity with J774A cells occurred in a local system as well as in a systemic system.

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