Hydrogen bonding interactions of polyamines with the 2′ OH of RNA
Open Access
- 1 April 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 5 (4) , 1315-1324
- https://doi.org/10.1093/nar/5.4.1315
Abstract
Polyamines and other charged amines bind to RNA by hydrogen bonding to the 3′ phosphate and to the 2′ OH. This mode of binding suggests a mechanism by which DNA and RNA might be distinguished by enzymes.Keywords
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