Abstract
The paper of Hage et al. [1] is an interesting study about the biology and the management of large-cell neuroendocrine carcinoma (LCNC) of the lung. The Authors emphasize the rarity of this tumour, and its correct inclusion within the neuroendocrine family of lung neoplasms, according to the recent Travis classification [2] and the immunohisyological staining characteristics.

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