Matrix metalloproteinases regulate neutrophil‐endothelial cell adhesion through generation of endothelin‐1[1–32]
Open Access
- 1 October 2001
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 15 (12) , 2230-2240
- https://doi.org/10.1096/fj.01-0178com
Abstract
We recently reported that matrix metal-loproteinase 2 (MMP-2, gelatinase A) cleaves big endo-thelin 1 (ET-1), yielding the vasoactive peptide ET-1[1–32]. We tested whether ET-1[1–32] could affect the...Keywords
Funding Information
- Medical Research Council Canada (MT-12573)
- Canadian Institutes of Health Research (MT-12573)
- Heart and Stroke Foundation of Canada
- Alberta Heritage Foundation for Medical Research
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