THE TREATMENT OF PEPTIC ULCER WITHOUT ALKALIS
- 3 January 1942
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 118 (1) , 38-41
- https://doi.org/10.1001/jama.1942.02830010040010
Abstract
The use of alkaline substances in the management of peptic ulcer is almost universal, and such treatment is recommended in nearly all the current textbooks dealing with the subject.1It is commonly assumed that complete neutralization of gastric acidity represents the ideal condition for ulcer healing, although no proof of this assumption exists. Furthermore, it is not certain that the highly alkaline stomach content obtained periodically in the course of alkali therapy is conducive to healing. That the conventional methods of treatment are not entirely satisfactory is manifest by the fact that scarcely a year passes without one or more new "ulcer treatments" being advocated. At frequent intervals new kinds of neutralizing agents, supposedly with better virtues or fewer evils, are recommended. The disadvantages of alkali therapy, which have been commonly recognized during its wide use, are: Alkalis may produce secondary acid secretion. Crohn and Reiss2stateKeywords
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