An 87-kilodalton glucan-binding protein of Streptococcus sobrinus B13
- 1 December 1992
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 60 (12) , 5291-5293
- https://doi.org/10.1128/iai.60.12.5291-5293.1992
Abstract
An 87-kDa glucan-binding protein (GBP) of Streptococcus sobrinus B13 (serotype d) was isolated and purified from extracellular culture supernatant by using affinity chromatography on Sephadex G-50 and elution with a guanidine HCl gradient. Western blot (immunoblot) analysis showed it to be antigenically related, but not completely identical, to the 74-kDa GBP of Streptococcus mutans Ingbritt. The 87-kDa GBP has no glucosyltransferase activity. A possible role for this GBP in the cariogenicity of S. sobrinus B13 is suggested.Keywords
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