Metal Complexes of Amino Acids. XII. The Deuteration of α-Hydrogen Atoms in Cobalt(III) Complexes Containing α-Amino Carboxylates
- 1 April 1980
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 53 (4) , 956-960
- https://doi.org/10.1246/bcsj.53.956
Abstract
The second-order rate constants (rate=kD(base)[Complex][OD−]) for the deuterium exchange of α-methylene or α-methine protons in the amino carboxylato complexes, trans(O)-, C1-cis(O)-, and C2-cis(O)-[Co(gly)2(en)]+ and -[Co(gly)2(tn)]+, [Co(gly)(NH3)4]2+, [Co(gly)(en)2]2+, [Co(gly)(tn)2]2+, [Co(sar)(en)2]2+, and Λ- and Δ-[Co(l-ala)(en)2]2+, were determined by the 1H-NMR measurement. The major factors determining the deuteration rate of α-hydrogens in the amino carboxylate chelate are the geometry and charge of the complex, and the nature of the substituent bonded to the chelate ring to be deuterated; the minor factor is the chelate-ring size of the ligands other than amino carboxylate in a complex molecule.Keywords
This publication has 23 references indexed in Scilit:
- Metal Complexes of Amino Acids. XI. Preparation and 13C NMR Spectra of the Cobalt(III) Complexes Containing β-Alanine and GlycineBulletin of the Chemical Society of Japan, 1979
- Proton magnetic resonance studies of pentadenate cobalt(III) aminocarboxylates. Structures and reactions of nitro- and aquo-substituted complexesInorganic Chemistry, 1971
- Complete assignment of nuclear magnetic resonance spectra of glycinate protons in cobalt(III)-aminocarboxylate chelatesInorganic Chemistry, 1971
- Cobalt(III) complexes with aminopolycarboxylic acids and nitrite ionInorganic Chemistry, 1970
- Nuclear magnetic resonance study of the .beta.-cis-ethylenediamine-N,N'-diacetatocobalt(III) chelate systemInorganic Chemistry, 1970
- Preparation of ethylenediamine-N,N'-diacetic-N,N'-di-.alpha.-propionic acid and the structure of its cobalt(III) complexInorganic Chemistry, 1969
- Nuclear magnetic resonance studies of rate and mechanism of stereospecific acid- and base-catalyzed deuterations of .alpha.-hydrogen atoms in ethylenediamine-N,N1-diacetatocobalt(III) chelatesInorganic Chemistry, 1968
- Proton exchange and mutarotation of chelated amino acids via carbanion intermediatesJournal of the American Chemical Society, 1967
- Cobalt(III)-Catalyzed Deuterium Exchanges on Ligands with Glycinate RingsInorganic Chemistry, 1966
- Selective Labilizing of α-Hydrogen Atoms by Chelation of α-Aminocarboxylic AcidsJournal of the American Chemical Society, 1965