Aldehydic peptides inhibiting renin
- 27 February 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 167 (2) , 273-276
- https://doi.org/10.1016/0014-5793(84)80141-6
Abstract
Aldehydic peptides in which the C terminal residue is leucinal or phenylalaninal were synthesized. These compounds exhibited potent inhibition of renin activity and appeared to be precursors of transition state analogues for renin-catalysed amide bond hydrolysisKeywords
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