VENOUS PRESSURE CHANGES ASSOCIATED WITH POSITIVE INTRAPULMONARY PRESSURES; THEIR RELATIONSHIP TO THE DISTENSIBILITY OF THE LUNG

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Abstract
Simultaneous measurements were made of peripheral venous pressure and of the intrapulmonary pressure developed when human subjects passively relaxed the chest at various lung volumes. Evidence is presented to show that the graphic relationship obtained from such data is useful for predicting the behavior of the mean peripheral venous pressure during various types of positive pressure breathing. A method for estimating the distensibility of the lungs from such measurements is also described. A value of about 0.5 cm. H2O/100 ml. change in lung volume is outlined.