Phuspholipase C Activity in Normal Rat Mammary Tissues and in DMBA-Induced Rat Mammary Tumors
- 1 March 1986
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 181 (3) , 450-453
- https://doi.org/10.3181/00379727-181-3-rc1
Abstract
Employing phosphatidylinositol as the substrate, phospholipase C (PLC) activity was measured in various cellular fractions derived from DMBA-induced rat mammary tumors and mammary tissues from 12-14 day pregnant rats. In the 2,000g pellet, 10,000g pellet, 100,000g pellet and 100,000g supernatant fractions, PLC activity was more than 5 fold higher in the fractions derived from the neoplastic tissues. This was true whether PLC activity was expressed on the basis of protein content or 5'' nucleotidase activities.This publication has 3 references indexed in Scilit:
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