The clinical use of C.A.B.B.S. renography. Investigation of the “non-functioning kidney” and renal artery stenosis by the use of131I Hippuran renography modified by computer assisted blood background subtraction (C.A.B.B.S.)

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Abstract
The 131I Hippuran renogram trace is impaired by the presence of extra-renal blood background. A method of blood background subtraction involving the use of a digital computer is introduced and examples of the use of the test are given in detecting unilateral renal artery stenosis and in the assessment of impaired renal function. Computer assisted blood background subtraction (C.A.B.B.S.) allows a more accurate estimation of the time to peak of the renogram. The time to peak depends on transit time and urine flow. C.A.B.B.S. allows the further analysis of the "non-functioning" standard renogram curve into those where up to 20% of renal function is revealed and those with a "nephrectomy" trace. It increases the usefulness of renography performed in patients with uremia and the results may have prognostic significance.

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