Enzymes involved in phenylalanine metabolism in the human foetus and child
Open Access
- 1 September 1973
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 26 (9) , 678-683
- https://doi.org/10.1136/jcp.26.9.678
Abstract
The activities of phenylalanine p-hydroxylase, tyrosine: alpha-ketoglutarate and phenylalanine: pyruvate aminotransferases, and aromatic alpha-ketoacid reductase have been measured in liver biopsies obtained from children with a series of disorders other than phenylketonuria and from human foetuses aged 8·5 to 24 weeks. The importance of such a study in relation to the management of infants with hyperphenylalaninaemia and pregnant phenylketonuric women is discussedKeywords
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