Differences in Rate and Variability of Intracellular Growth of a Panel ofMycobacterium tuberculosisClinical Isolates within a Human Monocyte Model
Open Access
- 1 November 2002
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 70 (11) , 6489-6493
- https://doi.org/10.1128/iai.70.11.6489-6493.2002
Abstract
Significant differences were observed in the capacities of Mycobacterium tuberculosis clinical isolates to grow within human monocytes. Genotyping indicated that the four most rapidly growing isolates were members of the Beijing strain family. M. tuberculosis strain H37Rv provided more reproducible infection than the clinical isolates or M. tuberculosis Erdman.Keywords
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